Bile Duct Cancer: Causes, Symptoms, and Treatment

Categories: HEALTH

Content Image

Bile Duct Cancer: Causes, Symptoms, and Treatment


Cholangiocarcinoma, another name for bile duct cancer, is an uncommon type of cancer that develops in the bile ducts. The digestive fluid known as bile is transported from the liver and gallbladder to the small intestine by a system of tubes called the bile ducts. In the small intestine, bile aids in the breakdown of lipids.




Other Names


Type of Cancer

Malignant (cancerous) tumor arising from the bile ducts


Network of tubes (bile ducts) that carry bile between the liver, gallbladder, and small intestine



Age of Onset

Typically affects adults in their 70s


DNA mutations in bile duct cells

Risk Factors

•Primary sclerosing cholangitis (hardening and scarring of bile ducts) 

•Chronic liver disease 

•Biliary tract problems at birth (e.g., choledochal cyst) 

•Liver fluke infection (parasitic worm)

• Inflammatory bowel disease (ulcerative colitis or Crohn's disease) 


• Diabetes 

• Smoking

Symptoms (may not appear until later stages)

• Jaundice (yellowing of skin and whites of the eyes) 

• Intense itching 

• Abdominal pain 

•Dark urine 

•Light-colored or greasy stools 


•Nausea and vomiting 

•Unexplained weight loss 



•Blood tests 

•Imaging tests (ultrasound, CT scan, MRI) 


Treatment (depends on stage and location of cancer)

• Surgery: Aim is to remove as much of the cancer as possible, may involve removing part of the bile duct, liver tissue, pancreas tissue, or lymph nodes. 

• Liver transplant: In some cases, a liver transplant may be an option. 

•Biliary drainage: Procedures to restore bile flow (e.g., stents, bypass surgery) 

•Chemotherapy: Uses drugs to kill cancer cells. • Radiation therapy: Uses high-energy rays to kill cancer cells. 

•Photodynamic therapy: Uses light to activate a drug that destroys cancer cells.


Varies depending on the stage and type of bile duct cancer. Early detection is crucial for better outcomes. 

Note: This table provides a general overview. It is important to consult with a healthcare professional for diagnosis and treatment specific to your situation.


Causes of Bile Duct Cancer


Although the precise causation of bile duct cancer is uncertain, bile duct cell DNA alterations are considered to be the cause. Numerous things can lead to these changes, such as:


•Primary sclerosing cholangitis: This is a chronic liver disease that causes inflammation and scarring of the bile ducts.

•Chronic liver disease: This includes conditions such as cirrhosis and hepatitis.

•Biliary tract problems at birth: A condition called choledochal cyst, in which the bile duct is abnormally dilated, is one of the birth malformations that can raise the risk of bile duct cancer.

•Liver fluke infection: Bile duct cancer risk is elevated by liver fluke, a parasitic worm infection that is more prevalent in several regions of the world, including Southeast Asia.

•Inflammatory bowel disease: Inflammatory bowel diseases such as Crohn's disease and ulcerative colitis can raise the risk of bile duct cancer.

•Obesity: Being overweight or obese is a risk factor for many types of cancer, including bile duct cancer.

•Diabetes: People with diabetes have an increased risk of bile duct cancer.

•Smoking: Smoking is a risk factor for many types of cancer, including bile duct cancer.


Symptoms of Bile Duct Cancer


Numerous symptoms are possible with bile duct cancer, though they might not show up until the disease is farther along. Among the most typical signs of bile duct carcinoma are:


•Jaundice: This is a yellowing of the skin and whites of the eyes that occurs when bile builds up in the bloodstream.

•Intense itching: This is a common symptom of bile duct cancer and can be very bothersome.

•Abdominal pain: Pain in the upper right abdomen is a common symptom of bile duct cancer.

•Dark urine: Urine may appear dark brown or tea-colored.

•Light-colored or greasy stools: Stools may be light-colored or greasy due to a lack of bile.

Top articles
The Advancements in Hydrogen Technology: What You Need to Know Published at:- The Impact of Post-Harvest Practices on Cocoa Drying Efficiency Published at:- 16 Habits for Successful Weight Loss Published at:- Understanding the Different Types of Diabetes and Their Symptoms Published at:- The Top 20 High-Sodium Foods to Avoid Published at:- The Importance of Hydration in Your Gym Diet Published at:- Understanding Schizophrenia: A Guide for Family and Friends Published at:- How Millets Can Help Manage Diabetes Published at:- Natural Weight Loss Pills: Are They Effective Published at:- The Top Most Common Foodborne Diseases and How to Avoid Them Published at:- The Benefits of Plant-Based Diets for Lowering Cholesterol and Cardiovascular Health Published at:- How to Recognize the Signs of Poor Bone Health Published at:- The Benefits and Drawbacks of Wearing a Bulletproof Jacket Published at:- The Silent Killer: Understanding Blood Clot Symptoms Published at:- How to Treat and Prevent Gum Disease Published at:- How to Identify When Your Heart Skips a Beat Published at:- Rh factor blood transfusion Published at:- Wrong Blood Type Transfusion Treatment Published at:- Thick Walled Gall Bladder Published at:- Kidney Transplant Blood Group Matching Published at:- Surgical Removal Of Gall Bladder Published at:- Blood Group Compatibility For Marriage Published at:- How Does Scabies Transmitted From One Person To Another Published at:- Belly fat reduce exercise Published at:- Weight loss diet plan for women Published at:- Diet plan for weight loss Published at:- Female cervical pain symptoms Published at:- Ten Personal Hygiene Practices Published at:- Indian Snacks Recipes Vegetarian Published at:- Iron Deficiency Symptoms in Nails Published at:- Cat Bite Infection Symptoms Published at:- Rocky Mountain Spotted Fever Tick Bite Published at:- Pulled Neck Muscle Can’t Turn Head Published at:- Best Antibiotic for Cat Bite Published at:- Danger Level of SGPT and SGOT Treatment Published at:- Thick White Discharge Published at:- hemorrhoid surgery Published at:- Delicious and Easy-to-Make Cocktails to Wow Your Guests at the New Year Party Published at:- Preventing Winter Illnesses Published at:- Understanding Walking Pneumonia: Symptoms, Causes, and Treatment Published at:- Deciphering Cervical Dystonia Symptoms: Untangling the Difficulties of an Uncommon Neurological Illness Published at:- Whole-System Chronic Bronchitis Therapy: A Manual for Efficient Care Published at:- Understanding RSV Virus in Adults: Symptoms, Treatment, and Prevention Published at:- Mastering the Smokey Eye for Winter: Step-by-Step Guide Published at:- Hydration The Key to Rescuing Your Lips from Winter Cracks Published at:- Winter Skincare Essential: Choosing the Perfect Moisturizer for Your Skin Published at:- 5 Warming Herbal Tea Recipes to Cozy Up Your Winter Evenings Published at:- Diagnosis and Treatment Options for HIV Virus Syndrome Published at:- Living with HIV: Treatment Options and Quality of Life Published at:- The Role of Education in HIV Prevention: World AIDS Day Awareness Published at:- Encouraging Lives: The International Fight against HIV/AIDS and International AIDS Day Published at:- Understanding the Basics: What is the HIV Virus? Published at:- Joe Biden Receives the Most Recent Covid 19 Vaccine Published at:- Haemorrhoid Surgery: When Surgery Becomes the Only Option Published at:- JN.1: The New COVID Variant on the Rise - What You Need to Know Published at:- Boost Your Energy Levels: Fasting Tips for Chaitra Navratri Published at:- Understanding Chagas Disease: Symptoms, Transmission, and Prevention Published at:- Exploring the Link Between Dry Mouth and Other Health Issues: Symptoms to Watch for in 2024 Published at:- Bile Duct Cancer: Causes, Symptoms, and Treatment Published at:-